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Feb
15
2001

Science as Dr. Frankenstein

I hope every single one of you realizes that “the perfect human” is a phrase completely devoid of meaning in a constantly changing world and universe.

I read an article yesterday in TIME magazine that made some good points about genetic engineering, and as I often do, I started thinking about this subject: scientists genetically engineering humans to make them supremely intelligent, strong, agile, wicked, purple, hermaphroditic, or a combination of the above. The article was called “Why Pro-lifers are missing the point” and its main argument was that the moral question of stem cell research should not be where the tissue is coming from (dead fetuses vs. embryos for in vitro fertilization), the question should be where it is going?

I think this is a very valid concern and it ought to give us pause to consider the implications of genetic engineering research. However, I’d like to tell you some of the things mentioned in the article that I believe are full of the proverbial “it”.

First,

“In 1998, Massachusetts scientists injected a human nucleus into a cow egg. The resulting embryo, destroyed early, appeared to be producing human protein, but we have no idea what kind of grotesque hybrid entity would come out of such marriage.”

What!!?? No “grotesque hybrid” could possibly come from this. Why? Because THERE IS NO COW DNA IN THE EGG, except for some maternal mitochondrial DNA. It was an enucleated egg, replaced with a human nucleus. The only thing that would happen is the embryo would die because there would not be the correct maternal mRNA for proper development. Besides where would the fetus gestate? You gonna keep it in a box?! (Thank you Monty Python) I seriously doubt that you could just stick it in a cow. First, the embryo would not be able to implant into the cow’s uterus. If it miraculously could, the cow’s body would more than likely detect a “problem” with the embryo and would reabsorb it or flush it.

Second,

“Last October, the first primate containing genes from another species – a monkey with a jellyfish gene – was born. Monkeys today. Tomorrow humans.”

This is true. I’ve seen pictures of the little rhesus monkey, and damn was he cute. I should note that although his chromosomes contained the green fluorescence protein gene, the gene was not expressed (meaning no protein was made and the gene was essentially just sitting there doing nothing). Yes humans are next. Big deal. Some of our genes were imported from other species into our own genome by retroviruses! What is better, random insertion of a random gene with an astronomically small chance of it helping an organism, or carefully planned and controlled introduction of a gene for a specific beneficial purpose with a much higher chance of success? You make the call.

Finally, the article says,

“but just around the corner lies the logical by-product of such research: the hybrid human-animal species, the partly developed human bodies for use as parts, and other grotesqueries as yet unimagined.”

As for the human-animal hybrids, in the not-too-distant-future this may become possible. However there would be very little incentive for this other than the “look what I can do” factor. What is so inherently “grotesque” about a species of organism that has some human and some animal aspects? Any hybrid we created wouldn’t be human. Humans are animals, therefore the new hybrid would simply be another species on this planet. God knows we’ve killed enough off already. I personally think it would be pretty amazing to have another intelligent species on this planet. Besides if people create animals with human intellect, it isn’t going to be for food or slavery. It almost seems preposterous to imagine, but I think it will not be so in a few generations.

It is very possible in the future that if animals continue to be exploited by humans for food, the animals will likely by made dumber and stripped of pain perception, which will make slaughter a little more like cutting down a tree.

Some of this technology may even allow us to replace some of the species we’ve already killed off.

Human bodies grown for body parts are not a “by-product” of this research. They are one of the ULTIMATE GOALS of this research. Do you realize how many people die every day because they can’t find a heart, lung, liver, or kidney donor? Now imagine if we could grow human bodies with no conscious, self-awareness, feelings, or even the brain structures to allow these things. It wouldn’t be a deformed grotesque human, it would be a TISSUE CULTURE for saving lives. This would be revolutionary. Tell me you won’t appreciate this in twenty years when your liver is an alcohol-ridden degraded soggy mass full of holes.

People think we’re trying to play God and that we are trying to do in a short time what it took nature billions of years to do. But nature is not an entity that sat here and thought “I wonder what would happen if I stuck feathers on that little lizard’s arms?” It took millions of failed mutations that led to grotesque deformities and sudden deaths for every single gene that benefits an organism. If you were to watch evolution through a time-lapse, it would not be a pretty sight (actually I think it would be fascinating and beautiful, but that’s just me) compared to what “grotesqueries” we might create.

Now I am not saying we should just start engineering things and cramming different genes in different organisms to see what we can sculpt. Life is not a toy and there are many, many, MANY obstacles to be overcome. We still don’t have a single descent way of introducing a gene into a human chromosome in a controlled way as to prevent the disruption of other genes or cause a myriad other problems. All our current techniques involve “shotgun techniques” shooting DNA into a nucleus, hoping the gene gets stuck in a good place on a random chromosome. Most of them involve using viral capsules (basically just containers with no viral DNA) to get the DNA into the cell, which is so far turning out to be very inefficient and unpredictable. This is not how human genetic engineering should be done. But as long as we (which includes everyone in the public) proceed which extreme caution, skepticism of all data and discoveries, and keep an OPEN MIND, then I will remain optimistic of the benefits that genetic engineering and stem cell research can do for our race.

At least the ones that can afford it.


Written by Irradiatus in
Categories: Biology, Evolution, Genetics, Science
Tags: ,

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